“JUST SOME DIZZINESS”, OR IS IT?

Swathi Rao, Fanny GIRON GALEANO, Benjamin Jang, Vaishak Amblee, Farah Ciftci, , Berwyn, IL

Meeting: Hospital Medicine 2019, March 24-27, National Harbor, Md.

Abstract number: 925

Categories: Adult, Clinical Vignettes, Hospital Medicine 2019

Keywords: , , ,

Case Presentation: IntroductionDizziness is one of the most frequent complaints encountered in the medical practice affecting 15-20% of adults yearly 1, and can be challenging to assess. Dizziness can be classified into vertigo, disequilibrium and syncope.
Most patients use dizziness as a non-specific term, and thus suffer prejudice from the physicians’ end and can be disregarded frequently. Dizziness can be a symptom of various diseases, some with sinister pathologies. We present a case of garden-variety vertigo that unfurled to be not-so-simple, emphasizing the importance of a thorough history and physical examination again even in the era of technology.
Clinical presentation
A 32-year-old male patient with no past medical history presented with dizziness, later clarified as gradually progressive vertigo for two years, with unstable gait, dysarthria, and occasional diplopia. Patient denied headache, nausea, vomiting, tinnitus, hearing loss, muscle weakness, seizures or loss of consciousness. Physical examination found sustained nystagmus that changed direction with horizontal gaze, vertical nystagmus with upward gaze, dysarthria, and a wide-based ataxic gait. CT head without contrast revealed indeterminate hypodense areas in the left midbrain, pons and cerebellar hemisphere. MRI brain identified a 2.8 x 3.4 x 4.2 cm Spetzler-Martin Grade IV brainstem arteriovenous malformation (AVM) involving the left midbrain, pons, and cerebellum. Feeders were mostly from the posterior circulation, with 3 intranidal aneurysms, all draining into the deep venous system. The AVM was deemed inoperable and the patient was treated with onyx embolization for 2/3 feeding vessel aneurysms. After treatment, the symptoms persisted, and the patient was diagnosed with Major Depressive Disorder (MDD) six months after diagnosis, and was admitted a year later with suicidal ideation and substance use disorder.

Discussion: Brain AVMs are a rare clinical entity present in 0.1% of the population.2 They are the most dangerous congenital vascular malformations, commonly presenting with intracranial hemorrhage (ICH) (41-79%) 3 or seizure (11-33%) 4,5. When they do rarely present with isolated focal neurologic deficits, it has been attributed to a vascular steal phenomenon, hemorrhage or a mass effect6.
The isolated findings of vertigo and dysarthria without hemorrhage or seizures such as in our patient are highly non-specific and have a multitude of differential diagnoses; with such presentation clinicians should consider etiologies under the realm of vertigo of central origin.

Conclusions: While approaching vertigo, a thorough history focused on duration and onset of the vertigo, and physical examination focusing on focal neurologic deficits, eye movements, nystagmus, cranial nerves and cerebellar exam are pivotal. An untreatable AVM reduces patients’ quality of life and has been linked to depression and anxiety7-10, and thus patients may benefit from psychosocial therapy. Although preventing ICH is the primary concern with brain AVMs, the rest of the patient’s profile should not be forgotten.

IMAGE 1: MRA sagital

IMAGE 2: MRI with contrast

To cite this abstract:

Rao, S; GIRON GALEANO, F; Jang, B; Amblee, V; Ciftci, F. “JUST SOME DIZZINESS”, OR IS IT?. Abstract published at Hospital Medicine 2019, March 24-27, National Harbor, Md. Abstract 925. https://www.shmabstracts.com/abstract/just-some-dizziness-or-is-it/. Accessed December 6, 2019.

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