Dettol Poisoning: A Case Report and Review of the Literature

1Changi General Hospital, Singapore, Singapore

Meeting: Hospital Medicine 2015, March 29-April 1, National Harbor, Md.

Abstract number: 537

Keywords:

Background:

Dettol liquid (4.8% chloroxylenol, pine oil, isopropyl alcohol) is a commonly used liquid disinfectant. Various effects have been associated with its ingestion and this includes central nervous system depression, airway obstruction, gastro-esophagitis and cardiac toxicity.

Methods:

A 52 year old man was admitted to the Intensive Care Unit following intubation for airway protection as a result of drowsiness and respiratory distress after he ingested 400ml of Dettol. He developed hypotension and was treated with intravenous fluids and started on ionotropic support. Electrocardiogram showed sinus tachycardia with a prolonged QTc of 650. He also developed acute kidney injury with normal anion gap metabolic acidosis. Blood and urine samples sent for formal toxicology analysis subsequently confirmed the presence of chloroxylenol, terpineol and isopropyl alcohol. The QTc and serum bicarbonate returned to normal limits following administration of intravenous fluids and isotonic bicarbonate. He did not require renal replacement therapy. His condition subsequently improved and he was successfully extubated 24 hours later. A post-extubation esophagoduodenoscopy showed esophagitis but no ulcerations.

Results:

Several case reports on Dettol ingestion demonstrate the development of upper airway obstruction necessitating airway intervention[1]. Gastro-esophagitis due to the corrosive nature of chloroxylenol is also often seen[2]. Less commonly, hypotension and metabolic acidosis can occur as a result of chloroxylenol and isopropyl alcohol toxicity[3]. Rarely, isopropyl alcohol can also result in cardiac dysrhythmias[3]. 

Conclusions:

A variety of complications, some of which may be life-threatening, can result from Dettol ingestion. It is therefore important to be cognizant of these so that interventions can be undertaken early.

1.            Lam, P.K., et al., Dettol poisoning and the need for airway intervention. Hong Kong Med J, 2012. 18(4): p. 270-5.

2.            Chan, T.Y., J.J. Sung, and J.A. Critchley, Chemical gastro-oesophagitis, upper gastrointestinal haemorrhage and gastroscopic findings following Dettol poisoning. Hum Exp Toxicol, 1995. 14(1): p. 18-9.

3.            Graham, C.A., Stridor after ingestion of dettol and domestos. Eur J Emerg Med, 2004. 11(1): p. 52-4.

To cite this abstract:

Hanif I, Chai H, Koh J. Dettol Poisoning: A Case Report and Review of the Literature. Abstract published at Hospital Medicine 2015, March 29-April 1, National Harbor, Md. Abstract 537. Journal of Hospital Medicine. 2015; 10 (suppl 2). https://www.shmabstracts.com/abstract/dettol-poisoning-a-case-report-and-review-of-the-literature/. Accessed July 20, 2019.

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